Overview

Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis

Status:
Completed

Trial end date:
1999-06-01

Target enrollment:

Participant gender:

Summary

OBJECTIVES: I. Determine the effect of different doses of ibuprofen on neutrophil (polymorphonuclear leukocyte; PMN) delivery to a mucosal surface (the oral mucosa) in patients with cystic fibrosis and healthy controls. II. Determine the duration of effect (and possible rebound effect) of ibuprofen on PMN delivery to a mucosal surface in these patients.

Phase:

N/A

Details

Lead Sponsor:

FDA Office of Orphan Products Development

Collaborator:

Case Western Reserve University

Treatments:

Ibuprofen