Study of Inhaled Nitric Oxide (iNO) and Respiratory Outcomes in Late Preterm Infants
Status:
Terminated
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to determine if inhaled nitric oxide will improve short and long
term respiratory outcomes in preterm infants. Infants born at a gestational age of 30-36
weeks and who require breathing support with high flow nasal cannula, nasal continuous
positive airway pressure, or nasal intermittent positive pressure will be randomized to
receive either inhaled nitric oxide or placebo. The dose will then be decreased per protocol
until all respiratory support has been discontinued. Infants will be followed to evaluate
safety and efficacy of non-invasive iNO delivery, up to 12 months corrected gestational age.