Overview

Study of KITE-197 in Participants With Relapsed or Refractory Large B-cell Lymphoma

Status:
Recruiting
Trial end date:
2027-12-01
Target enrollment:
Participant gender:
Summary
This study will have two Phases: Phase 1a and Phase 1b. The goal of Phase 1a of this clinical study is to learn more about the safety, tolerability and dosing of study drug KITE-197, in participants with relapsed or refractory large B-cell lymphoma (r/rLBCL). The goal of Phase 1b of this clinical study is learn about the effectiveness of the recommended dose of KITE-197 in participants with r/r LBCL. The primary objectives of this study are: Phase 1a: To evaluate the safety of KITE-197 in participants with r/r LBCL and determine the target dose level for Phase 1b. Phase 1b: To evaluate the efficacy of KITE-197 in participants with r/r LBCL as measured by the complete remission (CR) rate.
Phase:
Phase 1
Details
Lead Sponsor:
Kite, A Gilead Company
Treatments:
Cyclophosphamide
Fludarabine