Study of Lactobacillus in Adjuvant Treatment of RVVC

• Status: Recruiting
• Trial end date: 2023-06-30
• Target enrollment: 0
• Participant gender: Female

Summary

We are trying to determine if Clotrimazole vaginal tablets with oral Lactobacillus is better than Clotrimazole vaginal tablets in Preventing the Recurrence of vulvovaginalcandidiasis

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Peking University Shenzhen Hospital
• Treatments: Clotrimazole; Miconazole

Criteria

Inclusion Criteria:

• Women be at least 18 years of age

• Have symptoms of vulva irritation and or abnormal discharge

• Meet the clinical criteria for RVVC

• Willing to participate in research

Exclusion Criteria:

1. Taking / injecting antibiotics in the past two weeks;

2. A woman who intends to be pregnant, pregnant or lactating;

3. Long term use of contraceptives and immunosuppressants;

4. Postmenopausal;

5. There was no same fixed sexual partner (RSP) before and after treatment

6. Patients with severe gastrointestinal diseases, including colorectal cancer, IBS, IBD, chronic or acute diarrhea, long-term constipation, etc., or receiving gastrointestinal surgery and abdominal surgery within one year, such as cholecystectomy;

7. Patients with severe heart, liver and kidney dysfunction, mental diseases, infectious diseases, tumors, severe anemia, and severe autoimmune diseases (such as rheumatoid arthritis, lupus erythematosus, etc.)