Study of Levofloxacin-based Concomitant Therapy for H. Pylori Eradication in Diabetic Patients

• Status: Completed
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aims to evaluate H. pylori eradication rate in diabetic patients by using novel 10-day levofloxacin-based concomitant therapy compared with conventional 10-day sequential therapy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chung-Tai Wu
• Collaborator: Ministry of Health and Welfare, Taiwan
• Treatments: Amoxicillin; Clarithromycin; Levofloxacin; Metronidazole; Ofloxacin; Pantoprazole

Criteria

Inclusion Criteria:

• Diabetic patients with Helicobacter pylori infection

Exclusion Criteria:

• Pregnancy or physically poor performance status

• Patients with contraindication for upper endoscopy

• Severe coagulopathy for endoscopic biopsy

• Chronic kidney disease (eGFR < 50) or end stage renal disease

• Known allergy to interventional drugs

• Previous eradication failure