Study of Long-Term Use of Proton-Pump-Inhibitors in General Practice

• Status: Unknown status
• Trial end date: 2008-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary purpose of the study is to determine the effect of esomeprazole compared to placebo in patients from general practice who have previously been treated with proton-pump-inhibitors (PPI) and who have no upper endoscopic findings.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Glostrup University Hospital, Copenhagen
• Treatments: Esomeprazole; Proton Pump Inhibitors

Criteria

Inclusion Criteria:

• Treatment with PPI in at least 4 months out of the preceding 12.

• Use of PPI in the preceding 10 out of 30 days before inclusion

• Age above 18 years

Exclusion Criteria:

• Erosive Esophagitis

• PPI-treatment as prophylaxis against gastrointestinal bleeding

• PPI-treatment as prophylaxis against ulcers

• PPI-treatment as prophylaxis because of NSAID-treatment

• Pregnant or lactating women

• Previous upper GI surgery