Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC
Status:
Active, not recruiting
Trial end date:
2023-04-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn if olaparib, when given after treatment
with cabazitaxel, carboplatin, and prednisone, can help to control aggressive variant
prostate cancer (AVPC). The safety of these drugs will also be studied.
This is an investigational study. Cabazitaxel and carboplatin are FDA approved and
commercially available for the treatment of certain types of prostate cancer. Prednisone is
FDA-approved and commercially available as a corticosteroid. Olaparib is FDA approved and
commercially available for the treatment of certain types of ovarian cancer. The combination
of cabazitaxel and carboplatin followed by olaparib in this study is investigational.
The study doctor can describe how the study drugs are designed to work.
Up to 96 participants will be enrolled on this study. All will take part at MD Anderson.