Overview

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

Status:
RECRUITING
Trial end date:
2028-05-01
Target enrollment:
Participant gender:
Summary
This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-341 administered orally as a single agent or combination therapy in patients with microsatellite instability high (MSI-H) or DNA mismatch repair deficiency (dMMR) solid tumors.
Phase:
PHASE1
Details
Lead Sponsor:
MOMA Therapeutics
Treatments:
Immunotherapy
Irinotecan