Study of PK/PD, Safety and Tolerability of LIK066 in Patients With Decreased Renal Function.
Status:
Completed
Trial end date:
2018-01-16
Target enrollment:
Participant gender:
Summary
The purpose of this trial was to evaluate whether the study drug, LIK066, causes glucose
excretion in urine in patients with varying degrees of decreased kidney function and in
subjects with normal kidney function. Blood samples were collected to measure the
concentrations of LIK066 and to study the pharmacokinetics of LIK066. Pharmacokinetics is
meant to study how LIK066 is absorbed, distributed and eliminated, in other words what the
body does to the drug. The results of this study may be used to help determine whether LIK066
can be used to treat people with reduced kidney function and the proper dosing regimen.