Study of Pharmacotherapy of Psychotic Depression

• Status: Completed
• Trial end date: 2008-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine the effectiveness of combining selective serotonin reuptake inhibitors (SSRIs) with antipsychotic medications in the treatment of psychotic depression.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Weill Medical College of Cornell University
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Antipsychotic Agents; Olanzapine; Serotonin Uptake Inhibitors; Sertraline

Criteria

Inclusion Criteria:

• Major depressive disorder, single or recurrent, with psychotic features

Exclusion Criteria:

• History of substance abuse or dependence within the 3 months prior to enrollment

• Acute or unstable medical illness

• Diagnosis of schizophrenia or other psychotic disorders

• Pregnant

• Intolerance to SSRIs or olanzapine