Study of Phenobarbital Inhibition of Catamenial Epilepsy
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the effectiveness of low-dose Phenobarbital on the
treatment of catamenial epilepsy.
We propose that since the catamenial seizures are associated with the reduction in levels of
GABA-enhancing allopregnanolone, short-term replacement with the GABAR-enhancing agent
Phenobarbital will reduce the incidence of catamenial seizures.