Study of Povidone Iodine to Reduce Pulmonary Infection in Head Trauma and Cerebral Hemorrhage in Intensive Care Unit
Status:
Terminated
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
Head trauma and severe cerebral hemorrhage are major risk factors for development of
ventilator-associated pneumonia. In a previous open labelled, single center study the
investigators showed that repeated oropharyngeal decontamination with povidone-iodine may be
an effective strategy to decrease the prevalence of ventilator-associated pneumonia in
patients with head trauma. The present study aims to confirm these results in a multicenter,
double blind study including patients suffering from head trauma or cerebral hemorrhage.