Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary Bladder
Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether pralatrexate, given with vitamin B12 and
folic acid, is effective in the treatment of advanced or metastatic bladder cancer. The study
will also investigate the safety of pralatrexate with vitamin B12 and folic acid in this
patient population. Additionally, this study includes the collection of blood samples to
investigate the pharmacokinetics (PK) of pralatrexate in this patient population (PK is the
activity of a drug in the body over a period of time, including how the drug is absorbed,
distributed in the body, localized in the tissues, and excreted from the body).