Study of Relationship Between UGT1A1 Gene Polymorphism and Toxicity and Efficacy of Irinotecan in Small Cell Lung Cancer

• Status: Unknown status
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to find out the correlation between uridine diphosphate glucuronosyl transferase 1A1(UGT1A1) gene polymorphisms and the side effect and efficacy of irinotecan in patients with small cell lung cancer.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Zhejiang Cancer Hospital
• Treatments: Camptothecin; Irinotecan

Criteria

Inclusion Criteria:

• Clinical diagnosis of refractory or relapsed small cell lung cancer

• Physical examination and routine laboratory tests show no contraindications to chemotherapy

Exclusion Criteria:

• Pregnant and nursing women

• Brain metastasis with symptoms