Overview

Study of Sorafenib and Transarterial Chemoembolization (TACE) to Treat Hepatocellular Carcinoma

Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
This study will combine two therapies to treat patients with unresectable hepatocellular carcinoma; sorafenib, and drug eluting beads delivered intra-arterially. The purpose of the study is to establish the safety and the effectiveness of the combination therapy. The investigators hypothesize that the combination of the two therapies will not result in greater toxicities to patients than that expected for either therapy given alone.
Phase:
Phase 2
Details
Lead Sponsor:
Sidney Kimmel Comprehensive Cancer Center
Yale University
Collaborators:
Bayer
Biocompatibles UK Ltd
Treatments:
Doxorubicin
Liposomal doxorubicin
Niacinamide
Sorafenib