Study of T3 for the Treatment of Fibromyalgia

• Status: Completed
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Determine if T3 - the active form of thyroid hormone - is beneficial in fibromyalgia. Determine the feasibility and promise of an appropriately powered future prospective randomized controlled study of using T3 (the active form of thyroid hormone) for the treatment of fibromyalgia. We specifically aim to assess the feasibility, cost, obstacles and promise of conducting a prospective controlled study in the future.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stanford University

Criteria

Inclusion Criteria:

1. Age 18-50

2. Meet american college of rheumatology criteria for fibromyalgia

3. at baseline report an average pain of 4 or more on a brief Pain Inventory.

4. can climb 2 flights of stairs without shortness of breath.

Exclusion Criteria:

1. new medication change in the last 2 months

2. any cardiac disease at all

3. known thyroid disease before or after thyroid screening bloodwork

4. unstable medical or psychiatric disease.

5. Known inflammatory or rheumatic disease other than fibromyalgia

6. substance abuse in the last year

7. suicidality or depression as indicated by a Beck Depression Inventory of 30 or above

8. concomitant herbal medications

9. multiple severe medication allergies

10. the assessment of the research team that inclusion of the subject could in some way compromise the safety and validity of the study.

11. diabetes

12. smoking

13. Known uncontrolled hypertension

14. known uncontrolled hypercholesterolemia