Overview

Study of Trametinib and Nab-paclitaxel in Patients With Melanoma

Status:
Withdrawn
Trial end date:
2016-01-20
Target enrollment:
Participant gender:
Summary
This study will investigate the combination of two drugs, trametinib and nab-paclitaxel, in patients with advanced unresectable or metastatic melanoma. Each drug has shown activity in trials of patients with melanoma. However, the combination of these two drugs has not been studied. In this trial the investigators will determine the maximum dose of the drug combination to be administered to patients with advanced unresectable or metastatic melanoma and examine the safety profile of the drug combination.
Phase:
Phase 1
Details
Lead Sponsor:
SCRI Development Innovations, LLC
Collaborators:
Celgene
Celgene Corporation
GlaxoSmithKline
Treatments:
Albumin-Bound Paclitaxel
Paclitaxel
Trametinib