Overview

Study of Tretinoin Capsules in Combination With Azacitidine and Venetoclax in Treatment Nave Participants With Acute Myeloid Leukemia

Status:
NOT_YET_RECRUITING
Trial end date:
2030-12-15
Target enrollment:
Participant gender:
Summary
This study was a prospective, two-arm, multicenter clinical trial to evaluate the efficacy and safety of tretinoin capsules combined with azacitidine and venetoclax in the treatment of newly diagnosed acute myeloid leukemia. Azacitidine, venetoclax, and tretinoin may arrest cancer cell growth by demethylation, promoting cell differentiation, or killing cells, while reducing blood-related adverse effects by promoting cell differentiation.
Phase:
NA
Details
Lead Sponsor:
The First Affiliated Hospital of Soochow University