Study of Two Different Starting Doses of Methotrexate When Starting Treatment in Rheumatoid Arthritis
Status:
Completed
Trial end date:
2012-07-01
Target enrollment:
Participant gender:
Summary
To use different starting doses of methotrexate (7.5 mg per week) versus 15 mg per week in
patients with rheumatoid arthritis, followed by similar hiking up of dose (2.5 mg per 2
weeks, till max of 25 mg per week). To look at the effect on efficacy ( or speed of efficacy)
versus the adverse effects.
Hypothesis: There will be no difference in the adverse effects, but better and faster control
of disease when starting with a higher methotrexate dose
Phase:
Phase 4
Details
Lead Sponsor:
Postgraduate Institute of Medical Education and Research