Study of Varencline Effects on Cigarette Smoking Reward and Craving During a Model of Brief Quit Attempt

• Status: Withdrawn
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Study of varenicline 2.0 mg/day treatment for 2 weeks with smoking test done in laboratory on Day 8 and a 1 week quit attempt from Day 8-14.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: New York University School of Medicine; NYU Langone Health
• Collaborator: Pfizer
• Treatments: Varenicline

Criteria

Inclusion Criteria:

• At least 10 cigarettes/day

• Interest in quitting smoking

• Willgness to comply with overnight smoking abbstiennce period followed by lab smoking test

Exclusion Criteria:

• Pregnancy

• Axis I psychiatric disorder which require treatment with psychoactive medication and would make study compliance difficult.

• Clinically significant medical condition in opinion of study clinician

• Drug or alcohol dependence inlast 12 months

• Use of other smoking cessation medications ot treatment progams in last 2 months