Study of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma Patients

• Status: Completed
• Trial end date: 2013-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Most of the patients under long application of anti-glaucoma eyedrops endure severe ocular surface irritation, which interrupt their quality of life a lot. Lots of studies aimed to search for new drugs for therapy. The investigators hypothesized that the artificial tears containing vitamin A or carbomer may be a great substitute. Both of the two drugs were in common use and had already been tested in animals.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Xiaodong Zhou
• Treatments: Carbopol 940; Retinol palmitate; Vitamin A; Vitamins

Criteria

Inclusion Criteria:

• diagnosed primary open-angle glaucoma or normal tension glaucoma patients with prostaglandin analogs treatment for more than one year.

Exclusion Criteria:

1. any systemic diseases which may cause ocular damage;

2. previous ocular trauma or surgery;

3. contact lens wear history in previous 6 months;

4. application of any artificial tears 3 months ago;

5. allergic to any of the drugs we used during examination.