Study of Vitamin D in Children With Sickle Cell Disease
Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
This pilot study aims to answer the question whether monthly oral vitamin D3 supplementation,
100,000 IU, will be safe and effective in raising serum 25-hydroxyvitamin D (form of vitamin
D measured in the blood) to levels considered sufficient (30 ng/mL) but well below the
threshold for toxicity (150 ng/mL) in children with sickle cell disease. Information from
this study will be crucial before we perform a larger clinical trial to determine the effects
of vitamin D in reducing respiratory complications in patients with sickle cell disease.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Gary M Brittenham, MD
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins