Study of Vitamin D in Untreated Metastatic Colorectal Cancer
Status:
Completed
Trial end date:
2019-11-09
Target enrollment:
Participant gender:
Summary
The Vitamin D receptor is found in colon cancer cells. When Vitamin D binds to the receptor
in the cancer cells, it may stop cancer cells from growing abnormally and may cause cell
death. Vitamin D has been used in other research studies and information from those other
research studies suggests that Vitamin D may help in the treatment of colorectal cancer.
In this research study, the investigators are comparing standard and higher dose Vitamin D
treatment when given in combination with standard treatment for metastatic colorectal cancer.
Standard treatment includes the chemotherapy combination of 5-FU, Leucovorin and Oxaliplatin
(FOLFOX) with bevacizumab.
Phase:
Phase 2
Details
Lead Sponsor:
Dana-Farber Cancer Institute
Treatments:
Bevacizumab Ergocalciferols Fluorouracil Leucovorin Oxaliplatin Vitamin D Vitamins