Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery

• Status: Completed
• Trial end date: 2000-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether a single, pre-operative dose of cefuroxime is effective in preventing surgical site infection in patients undergoing surgery for herniated disk

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre Hospitalier Universitaire Vaudois
• Collaborators: GlaxoSmithKline; University Hospital, Geneva
• Treatments: Cefuroxime; Cefuroxime axetil

Criteria

Inclusion Criteria:

• Age older than 18

• spinal surgery for herniated disk

Exclusion Criteria:

• known or suspected hypersensitivity to cephalosporins

• type I hypersensitivity to betalactamic antibiotics

• severe renal function impairment

• acquired immune deficiency syndrome (AIDS) or other conditions of severe immuno-suppression

• antibiotic therapy for concomitant infection at the time of surgery

• pregnancy

• refusal to participate