Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments

• Status: Completed
• Trial end date: 2005-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

This randomised controlled trial aimed to verify whether directly observed single dose treatment (with tinidazole+fluconazole) would be as effective as the longer standard treatments (metronidazole for 7 days, plus vaginal clotrimazole for 3 days) in the syndromic management of women presenting with vaginal discharge in primary health care centers of Ghana, Togo, Guinea and Mali. It was designed as an effectiveness trial, i.e. it was done under conditions typical of routine work in these health centers

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Université de Sherbrooke
• Collaborator: Canadian International Development Agency
• Treatments: Clotrimazole; Fluconazole; Metronidazole; Miconazole; Tinidazole

Criteria

Inclusion Criteria:

• women consulting for vaginal discharge

• local resident

• willingness and ability to consent

Exclusion Criteria:

• sex worker consulting for active screening

• main complaint of lower abdominal pain

• allergy to one of the study drugs