Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain
Status:
Completed
Trial end date:
2017-06-01
Target enrollment:
Participant gender:
Summary
Pain is very common in persons with a history of addiction, but few studies have examined the
best treatment of pain in this population. This is a study to determine the pain relief
provided by intravenous hydromorphone (Dilaudid) or buprenorphine given to persons maintained
on stable doses of methadone or buprenorphine who have chronic musculoskeletal pain.
Experimental sessions will require overnight stays on a residential research unit. In these
sessions, persons will be exposed to standard experimental pain techniques at baseline and
then rate the relief (if any) provided by the study medication when exposed to the same
techniques. Persons will be asked to participate in 3 sessions, each separated by at least 7
days.