Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance
Status:
Completed
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
Pain is very common in persons with a history of addiction, but few studies have examined the
best treatment of pain in this population. This is a study to determine the pain relief
provided by intravenous hydromorphone (Dilaudid) or buprenorphine given to persons maintained
on stable doses of methadone or buprenorphine. Experimental sessions will require overnight
stays on a residential research unit. In these sessions, persons will be exposed to standard
experimental pain techniques at baseline and then rate the relief (if any) provided by the
study medication when exposed to the same techniques. Persons will be asked to participate in
2 or 3 sessions, each separated by at least 7 days.