Overview

Study on Anti-inflammatory Effect of Anti-hypertensive Treatment in Patients With Small AAA's and Mild Hypertension

Status:
Terminated
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Inflammation of the blood vessel plays an important role in the development and growth of a dilated abdominal aorta. An elevated blood pressure leads to an increase in inflammation, therefore blood pressure lowering is an important part of the treatment of patients with a dilated abdominal aorta who also have an elevated blood pressure. In the investigators study the investigators compare the anti-inflammatory effects of 2 different blood pressure lowering strategies. The investigators hypothesize that both strategies will decrease inflammation, however the investigators believe the total decrease of inflammation depends on the type of blood pressure lowering medication used.
Phase:
N/A
Details
Lead Sponsor:
VU University Medical Center
Collaborator:
Novartis
Treatments:
Amlodipine
Hydrochlorothiazide