Study on Early Stage Bulky Cervical Cancers

• Status: Unknown status
• Trial end date: 2018-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to establish the role of neoadjuvant chemotherapy and chemo irradiation in carcinoma cervix and to compare its results with the concurrent chemo irradiation in terms of overall survival, disease free survival and quality of life.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rajkumar Kottayasamy Seenivasagam
• Treatments: Cisplatin; Paclitaxel

Criteria

Inclusion Criteria:

1. Patients with histologically confirmed bulky cervical Squamous cell carcinoma (FIGO stage IB2, II A2, IIB).

2. Age 18-60 years

3. Karnofsky performance status of ≥70%; ECOG PS ≤ 2

Exclusion Criteria:

1. Nonsquamous Histologies

2. Other systemic diseases, comorbidities precluding full participation in the study

3. Concomitant treatment with any experimental drug

4. Pregnant or nursing women

5. Previous or concomitant malignant diseases other than non-melanoma skin cancer

6. Previous radiation to the pelvis