Study on the Antiviral Therapy and Immune Reconstitution of Chinese HIV/AIDS Patients
Status:
Unknown status
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
This study will recruit 520 treatment-naive and 150 treatment-experienced patients to take
the first line or second line of antiviral therapy. This study aims to set up a well-trained
clinical and laboratory team in China, to explore the effects and side-effects of the
first-line and the second line of ARV treatment in Chinese HIV/AIDS adult patients, to
investigate the side-effects of ARV drugs, such as hepatotoxicity, lipoatrophy,
cardiovascular influence, to explore the pharmacokinetics/pharmacodynamics (PK/PD) of Chinese
generic ARV regiments and effective drug concentrations and to explore primary and secondary
drug resistance in China and the immune reconstitution characters of long term ARV in Chinese
adult AIDS patients. This study might provide more practical and optimizing prove for the
treatment guideline for resource limited areas.
Phase:
Phase 4
Details
Lead Sponsor:
Peking Union Medical College
Collaborator:
Ministry of Science and Technology of the People´s Republic of China