Study on the Effect of Two Ways of Cycloplegia on Biological Parameters of Ciliary Muscle
Status:
Not yet recruiting
Trial end date:
2023-01-01
Target enrollment:
Participant gender:
Summary
Atropine has a ciliary muscle-paralysing effect and causes hyperopic drift. Besides, atropine
has been proven to slow the progression of myopia. Many studies have suggested that atropine
can increase the thickness of the choroid. However, few studies have discussed changes in the
ciliary muscle after treatment with atropine or other cycloplegic agents.
This study aimed to assess the difference in ciliary muscle morphology before and after two
different cycloplegic agents and to analyze the correlation between the changes of ciliary
muscle biological parameters and the changes of eye axis, spherical equivalent, lens diopter,
choroidal thickness, etc. One hundred and forty-four children would be randomly assigned 1:1
to the 1% atropine group and the tropicamide group. This study might provide clinical
evidence for the role of regulatory factors in the occurrence and development of myopia.
Phase:
Phase 4
Details
Lead Sponsor:
Shanghai Eye Disease Prevention and Treatment Center