Study on the Effects of Exogenous Testosterone on Threat Perception and Behavioral Avoidance

• Status: Completed
• Trial end date: 2012-04-01
• Target enrollment: 0
• Participant gender: Male

Summary

The study aims to establish a clear causal link between testosterone and threat perception and behavioral responses to threat. Namely, the study focuses whether high levels of testosterone will cause an individual to exhibit increased physiological responses to threat (e.g., increased blood pressure, heart rate, and endocrine responses) and a decreased behavioral response (e.g., ignoring the threat, avoiding the threat, and postponing dealing with the threat). The threat in this study is a social threat involving public speaking, and is an outgrowth of previous research on the avoidance of health threats.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Texas at Austin
• Treatments: Methyltestosterone; Testosterone; Testosterone 17 beta-cypionate; Testosterone enanthate; Testosterone undecanoate

Criteria

Inclusion Criteria:

• Male

• In good health

• Aged 18-35

Exclusion Criteria:

• Female

• Known carcinoma of the breast or prostate

• Known sensitivity to alcohol or soy products

• Preexisting cardiac, renal, or hepatic diseases

• Obesity

• Chronic lung diseases

• Cancer

• Use of anticoagulants

• Use of insulin or a history of diabetes

• Use of corticosteroids

• High levels of physical contact with women or children

• Preexisting liver problems