Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Urgent Surgery

• Status: Unknown status
• Trial end date: 2020-08-15
• Target enrollment: 0
• Participant gender: All

Summary

The main objective is to study the efficacy of topical antibiotic therapy with Amoxicillin / Clavulanic acid in the prevention of surgical wound infection in patients undergoing emergency surgery for intra-abdominal infection

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universitat Internacional de Catalunya
• Collaborator: Hospital de Granollers
• Treatments: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Clavulanic Acids

Criteria

Inclusion Criteria:

• Patients over 18 years of age.

• Patients who require urgent surgical intervention and who come from the emergency service

• Patients affected by complicated intra-abdominal infection with peritonitis of more than one abdominal compartment or intra-abdominal abscess requiring open surgical intervention.

Exclusion Criteria:

• Women patients with positive pregnancy test.

• Patients with primary peritonitis and liver cirrhosis.

• Patients who have received antibiotic treatment during the 72 hours prior to the surgical intervention (except that administered to UCIES as a treatment dose of the same process)

• Patients allergic to the antibiotic used in the study.

• Patients who have undergone a surgical procedure of recently opened abdomen (up to 30 days before surgery), a prosthesis of synthetic material (mesh) or to which the surgical wound can not be closed according to the surgeon's criteria.

• Patients with an unfavorable life prognosis (ASA 5).