Overview

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309

Status:
Not yet recruiting
Trial end date:
2028-10-04
Target enrollment:
Participant gender:
Summary
This is a Phase 1a/1b, first-in-human (FIH), open label study to evaluate the safety, tolerability, and pharmacokinetics (PK) of PMC-309, a mAb against the human VISTA ligand, in participants with advanced or metastatic solid tumors administered as a monotherapy and in combination with pembrolizumab.
Phase:
Phase 1
Details
Lead Sponsor:
PharmAbcine
Collaborators:
Merck Sharp & Dohme LLC
Novotech (Australia) Pty Limited
Treatments:
Pembrolizumab