Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone.
Status:
Completed
Trial end date:
2005-06-01
Target enrollment:
Participant gender:
Summary
This study was developed in order to assess the effects of risperidone (Risperdal) as
compared with placebo on cognitive-motor performance (attention, memory, and hand steadiness)
and body movements.
We propose to study the effects of risperidone on cognitive-motor performance in children
already medicated for severe conduct problems. We would also like to look at safety by
assessing these children for dyskinetic movements. We already have a sizable cohort of
children maintained on risperidone. Our hypotheses are as follows:
1. Risperidone will have no adverse effects on cognitive-motor performance in children who
have received maintenance therapy for 4 to 20 months.
2. Children tested during placebo will show no more dyskinetic movements than during
risperidone treatment (i.e., there will be no unmasking of tardive dyskinesia).