Study to Evaluate The Analgesic Efficacy and Safety of Intravenous Paracetamol in Subjects With Postoperative Pain After Total Hip Arthroplasty

• Status: Completed
• Trial end date: 2008-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The main purpose is to evaluate the analgesic efficacy of 1g of intravenous (Iv) paracetamol versus i.v. placebo, administered every 6h, as measured by the reduction of the 24-hour cumulative dose of the opioid tramadol in the treatment of postoperative pain following total hip arthroplasty.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bristol-Myers Squibb
• Treatments: Acetaminophen; Analgesics

Criteria

Inclusion Criteria:

• Spinal anesth

• BMI 10-35

• No pain conditions/concom med may alter pain quantif.

Exclusion Criteria:

• Other add. surgery

• Liver/Renal function altered

• coagulation alterations

• Respir / Cardiac insufficiency

• Agents affecting microsomal syst