Study to Evaluate the Effect of Injection Lypolysis (Lipodissolve) Treatments to Reduce Body Fat
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
The combination of phosphatidylcholine (PPC) and deoxycholate (DC) injected into subcutaneous
fat is often popularly referred to as "Lipodissolve" therapy. Despite its attractiveness as
an easy and noninvasive cosmetic treatment, the safety, effectiveness, and how the injections
might work remain unclear. This study will investigate the hypothesis that injections of
PPC/DC will reduce the amount body fat in the treated area. If so, the mechanisms responsible
for the fat loss will be explored to find out whether fat cells die from toxic effects or are
broken apart by the PPC/DC. Patients will receive at least 2 (no more than 4) treatments with
PPC/DC injections every 2 months. Several methods of measuring fat loss will be used in the
study, including photography and measurement of patients, tissue biopsy, blood tests, and
MRI. The study will also record side effects of the treatments as well as patient
satisfaction.