Overview

Study to Evaluate the Effect of Naltrexone and Bupropion Combination on the Pharmacokinetics of Metformin in Healthy Participants

Status:
Completed

Trial end date:
2016-08-01

Target enrollment:

Participant gender:

Summary

The purpose of this study is to determine the effect of multiple oral doses of naltrexone/bupropion on the pharmacokinetics (PK) of a single oral dose of metformin.

Phase:

Phase 1

Details

Lead Sponsor:

Orexigen Therapeutics, Inc

Treatments:

Bupropion
Bupropion hydrochloride, naltrexone hydrochoride drug combination
Metformin
Naltrexone