Study to Evaluate the Effect of a Nu Skin Product and Device for Brown Spots

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether a topical Nu Skin product with or without a galvanic spa device improves brown spots on the face. The Nu Skin product will be compared to an over the counter moisturizer and tretinoin cream.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Massachusetts General Hospital
• Treatments: Tretinoin

Criteria

Inclusion Criteria:

• Able to understand and sign informed consent.

• Able to complete study and comply with study procedures.

• Caucasian female ages 25-55.

• Presence of photodamage and lentigines of II-III on the Glogau Photoaging

• Must be willing to avoid laser and light treatments, treatments with filler, chemical peels, microdermabrasion, Botox or any other cosmetic treatment to the face during the duration of the study.

• Must be willing to avoid changing topical moisturizers and cosmetics during the study.

• Able to stop any alpha or beta hydroxy acids, topical retinol or retinoid derivatives, topical antioxidants, or any topical product that may interfere with the study 2 weeks prior to the study.

Exclusion Criteria:

• Cosmetic treatment of face, such as laser or light treatment, filler, Botox, microdermabrasion, or chemical peels 6 months prior to study or during study.

• Current smoker.

• Pregnant, nursing, or planning to become pregnant during study.

• Currently taking drugs including oral retinoids or any other medication with a known clinically significant drug interaction with topical tretinoin.

• Known hypersensitivity to retinoids. History of severe retinoid dermatitis.

• History of substance abuse, mental dysfunction, or other factors limiting ability to cooperate with study.

• Concurrent participation in another clinical study or participation 30 days prior to enrollment that includes exposure to an investigational drug that would interfere with this study.

• Any disease or condition which would interfere with study participation or unduly increase risk.

• Presence of an electrically sensitive support system such as a pacemaker.

• Known history of epilepsy.

• Presence of metal implants or metal braces on teeth.