Study to Evaluate the Efficacy of Tetracycline in Epidermolysis Bullosa

• Status: Withdrawn
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Epidermolysis Bullosa(EB) is an inherited bullous disease. Tetracycline is believed to have anti inflammatory properties. 20 patients with EB older than 13 years will be treated for 4 months with tetracycline or placebo. After one month of wash out they will be treated for additional 4 m with placebo or tetracycline. The patients will be examined each month to estimate bulla formation,rate of healing .

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rambam Health Care Campus
• Treatments: Tetracycline

Criteria

Inclusion Criteria:

• diagnosed as epidermolysis bullosa

• not pregnant

• active disease

• more than 5 bulla-

Exclusion Criteria:

• age less than 13

• known sensitivity to tetracyclin

• abnormal liver and kidney tests.