Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse
Status:
Completed
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
This is a single-center, randomized, 7-way crossover, double-blind, active and
placebo-controlled study to evaluate the subjective effects of oxycodone combined with
ultra-low dose naltrexone in comparison to oxycodone alone in non-physically dependent
subjects with a history of opioid abuse. Approximately 14 subjects will be randomized to one
of fourteen sequences selected from a balanced 7x7 Latin square design and its mirror image.