Study to Find Out the Appropriate Initial Dose of the Anticoagulant Drug Phenprocoumon
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Oral anticoagulation is often initiated in hospitalized patients. Although the therapeutic
range of phenprocoumon is narrow, the individual drug demands unfortunately vary greatly
between persons. Our group recently developed two dosing algorithms for the initiation of
anticoagulation based on clinical predictors such as age, gender, body weight and laboratory
values.
The aim of the proposed study is to prospectively evaluate the efficacy and safety of these
two algorithms in medical and orthopedic inpatients, as well as in a group of outpatients and
possibly in a geriatric collective.