Studying the Effects of Administration of Polyunsaturated Fatty Acids (PUFAS) of Omega-3 Series in Nicotine Dependence
Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
Nicotine dependence may prolong the exposure to toxic substances that cause various diseases.
The Central Nervous System (CNS) is consisted by a large amount of Polyunsaturated Fatty
Acids (PUFAS) from omega-3 serie. Omega-3 takes part in several actions, including the
modulation of dopaminergic neurotransmission. In its deficiency is detected a hypofunctioning
of the mesolimbic and mesocortical pathway, related to the reward system, involved on the
context of nicotine dependence. Treatment using dietary supplementation with omega-3 shows
improvements in several diseases, including mood disorders such as anxiety and depression.
The investigators hypothesis is that supplementation with these fatty acids can restore the
levels of omega-3 and could decrease nicotine dependence. The investigators objective is to
investigate a possible association between increased serum levels of omega-3 and the
reduction in nicotine dependence.