Sub-dissociative Ketamine for the Management of Acute Pediatric Pain
Status:
Completed
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
The proposed trial is a prospective, double blinded, randomized control trial with the
primary aim of determining whether a single, sub-dissociative dose of ketamine will decrease
the total narcotic requirements of pediatric patients requiring intravenous analgesia in an
urban emergency department (ED) compared to a group of patients who receive morphine alone
for pain management. Patients are randomized to receive either a single bolus of ketamine
(0.3 mg/kg) or a single bolus of morphine (0.05mg/kg). All subsequent pain management will be
accomplished using morphine. Patient, family member, and research staff pain scores will be
recorded, until 3 hours post study medication administration. Family members are contacted
via telephone 24 hours post-ED discharge, and again at 7 days post-hospital discharge, for
evaluation via Post Hospitalization Behavior Questionnaire. Narcotic equivalents will be
calculated for up to 3 hours post study medication administration and compared between the
ketamine and morphine groups.