Subarachnoidal Anesthesia: Dexmedetomidine vs Fentanyl Plus Hyperbaric Bupivacaine for Lower Abdomen Surgery
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
Dexmedetomidine, highly selective agonist for alpha-2 receptors, enhances the sensory and
motor block with prolonged postoperative analgesia without hemodynamic compromise.
OBJECTIVE: To evaluate effects of dexmedetomidine vs fentanyl with hyperbaric bupivacaine
spinal anesthesia for lower abdominal surgeries.
METHODS: double-blind, randomized, American Society Anesthesiologist classification (ASA) : I
- II, 18-65 years. F group (23 patients) received 25 mcg fentanyl, Group D (27 patients), 10
mcg dexmedetomidine with 12.5 mg hyperbaric bupivacaine . 0,02mgrs morphine / kg
intravenously if EVA≥4was administered in postoperative period. Hemodynamic variables and O2
saturation intraoperatively was recorded, EVA every 4 hours, side effects, sensory block,
motor, sedation and peripheral neurological manifestations of toxicity.