Subconjunctival Versus Direct Mitomycin C in Trabeculectomy
Status:
Completed
Trial end date:
2019-04-14
Target enrollment:
Participant gender:
Summary
Trabeculectomy is routinely used as a surgical treatment for open angle glaucoma. Success of
trabeculectomy is greatly augmented by the use of antimetabolites to inhibit wound healing,
specifically Mitomycin C (MMC). MMC can be applied to the eye at various sites,
concentrations and times. This study aims to compare the two application routes that are
commonly employed: subconjunctival pre-operative injection and intraoperative direct scleral
application in terms of IOP lowering effect, bleb appearance and complications.