Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section

• Status: Terminated
• Trial end date: 2018-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine if giving an injection of numbing medication at the incision at the end of cesarean will help control pain AFTER cesarean delivery. This study seeks to assess pain relief with incisional infiltration of local anesthetic during cesareans performed under spinal anesthesia also using intrathecal opioids. Participants will receive the usual regimen of pain medication in spinal anesthesia. At the end of the cesarean delivery, while the participants are still under the spinal medication, participants will receive an injection, at the incision, either numbing medication (with or without epinephrine) or sterile saline. After the cesarean delivery, participants will receive, by mouth, commonly prescribed pain medications - these medications are oxycodone (an opioid/ narcotic), acetaminophen (or more commonly known as Tylenol), and ibuprofen.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Montefiore Medical Center
• Treatments: Bupivacaine; Epinephrine; Epinephryl borate; Fentanyl; Morphine; Pharmaceutical Solutions; Racepinephrine

Criteria

Inclusion criteria:

• elective cesarean delivery

• planned spinal anesthesia

Exclusion criteria:

• Non-English speaking

• Urgent or emergent cesarean delivery

• Active labor [defined as: >4cm cervical dilation or regular contractions noted on tocometer (>2 contractions in a 10 minute period for 30 consecutive minutes)]

• Chronic antepartum opioid use

• History of substance abuse (alcohol or drug)

• Current tobacco use

• Chronic steroid use