Subcutaneous Nitroglycerin to Prevent Radial Artery Occlusion in Children
Status:
Not yet recruiting
Trial end date:
2025-07-01
Target enrollment:
Participant gender:
Summary
The primary objective of the study is to evaluate the vasodilative effect of subcutaneous
nitroglycerin to prevent radial arterial occlusion(RAO) after removal of the radial arterial
catheter in pediatric patients. The hypothesis of this study is that subcutaneous
nitroglycerin will decrease the incidence of radial arterial occlusion after radial arterial
catheter removal in pediatric patients by increasing the radial artery size and improving the
first-attempt success rate of radial artery cannulation. This is a single-center,
double-blind, randomized, placebo-controlled study comparing the effect of subcutaneous
nitroglycerin and saline on radial artery cannulation and catheter removal in pediatric
patients. Prior to the procedure, each patient will be randomized into either the control
arm, saline, or the study arm, nitroglycerin.