Sublingual Immunotherapy With House Dust Mite Extract in Asthmatic Children
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Asthma, the airway inflammatory disorder, is an important chronic disease in children. About
10~15% children are bothered with this. Allergens, such as house-dust mites (HDM), animal
dander (i.e. cats and dogs), and seasonal pollens, are often implicated as causative and
triggering factors of respiratory attacks in children with asthma. Among them, mites are the
most common indoor allergen associated with asthma worldwide.
It appears that SLIT is somewhat effective and safe. However, on the current evidence,
further studies are needed to define the indications, the duration of treatment and
therapeutic optimal dose of standardized allergen extracts in relation to efficacy and side
effects before it is recommended for routine clinical use. The objective of the present study
was to investigate the effects and safety of StaloralTM, the standardized extracts of D. pt.
and D. f., in asthmatic children allergic to HDM.