Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

• Status: Not yet recruiting
• Trial end date: 2024-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed as a randomized controlled trial with patients assigned to neuromuscular reversal with either sugammadex or neostigmine/glycopyrrolate reversal. The study will not be blinded to the anesthesiologist to allow for appropriate decision-making on timing and dosage of reversal. This is a single-center study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Emory University
• Treatments: Glycopyrrolate; Neostigmine

Criteria

Inclusion Criteria:

• Patients 2-17 years of age

• Diagnosis of acute appendicitis

• Patient undergoing laparoscopic appendectomy at Children's Healthcare of Atlanta- Egleston.

• Parent or Legal Authorized Representative willing to participate, able to understand and sign an informed consent

Exclusion Criteria:

• Patient with an allergy to Sugammadex or Neostigmine

• History of renal dysfunction

• Parent or legal guardian unwilling or unable or unable to understand the informed consent